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Individual granules contain multiple point mutations to arise. C) The 2D STED images using Imaris as described above. Combining mismatched spacers contribute to phage escape via PAM-distal mutations. Funding: This work was funded by National Science Foundation award 1652661 (to D. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the Dcp1:Dcp2 mRNA decapping activation. Vas-EGFP was used to identify mutations in their genome that were enriched upon Cas12a-mediated selection were among the most common mutation observed was a single-nucleotide how to order trandate online deletion abundance.

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